Table 3 Effect of B. crispa and its fractions on carrageenan induced paw edema in rats
From: Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa
Treatment | Dose (mg/kg) i.p | Initial paw volume (ml) | Paw volume at 3 hr | Increase in paw volume | % Inhibition |
|---|---|---|---|---|---|
Control | - | 0.96 ± 0.01 | 1.13 ± 0.05 | 0.170 | - |
B. crispa | 50 | 0.94 ± 0.03 | 1.04 ± 0.03 | 0.10** | 41 |
100 | 0.96 ± 0.04 | 1.02 ± 0.03 | 0.06*** | 65 | |
200 | 0.93 ± 0.03 | 0.99 ± 0.05 | 0.06*** | 65 | |
Hexane fraction | 50 | 0.95 ± 0.01 | 1.03 ± 0.02 | 0.08** | 53 |
100 | 0.95 ± 0.03 | 1.0 ± 0.01 | 0.05*** | 71 | |
Aqueous fraction | 50 | 0.98 ± 0.02 | 1.09 ± 0.02 | 0.11 | 15 |
Diclofenac sodium | 20 | 0.98 ± 0.04 | 1.02 ± 0.03 | 0.04*** | 76 |
Indomethacin | 20 | 0.96 ± 0.01 | 1.03 ± 0.02 | 0.07** | 59 |