Table 1 Effect of B. crispa extracts and some pure compounds isolated from the plant on acetic acid induced writhing in mice
From: Analgesic, anti-inflammatory and anti-platelet activities of Buddleja crispa
Treatment | Dose (mg/kg) | Number of writhing | % Protection |
|---|---|---|---|
Control | - | 73 ± 7 | - |
B. crispa | 50 | 33 ± 5** | 54 |
100 | 26 ± 3*** | 64 | |
Hexane fraction | 10 | 32 ± 2*** | 56 |
25 | 21 ± 2*** | 71 | |
Aqueous fraction | 50 | 38 ± 3** | 48 |
BdI-2 | 5 | 35 ± 3** | 52 |
10 | 18 ± 5*** | 75 | |
BdI-H3 | 1 | 49 ± 5* | 33 |
5 | 24 ± 4*** | 67 | |
BH-3 | 5 | 56 ± 6 | 23 |
10 | 48 ± 4* | 34 | |
Diclofenac sodium | 10 | 30 ± 6*** | 59 |
20 | 13 ± 5*** | 82 |