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Table 1 Effect of GXD on hemodynamic parameters and cardiac function induced by coronary artery ligation

From: Gualou Xiebai decoction inhibits cardiac dysfunction and inflammation in cardiac fibrosis rats

 

sham

MI

GXDL

GXDH

HR(beats/min)

359.6 ± 42.3

259.8 ± 29.5△△

306.0 ± 55.4*

333.7 ± 57.2**

SBP(mmHg)

107.1 ± 10.1

82.9 ± 7.7△△

88.4 ± 7.3

99.1 ± 10.2**

DBP(mmHg)

69.93 ± 10.47

56.48 ± 8.07△△

62.59 ± 5.26*

67.26 ± 11.65*

+LV dp/dtmax(mmHg/s)

5287.03 ± 1247.53

3312.07 ± 859.48△△

4062.42 ± 623.19*

4752.61 ± 930.10**

-LV dp/dtmin(mmHg/s)

4099.12 ± 759.61

3005.07 ± 517.25△△

3357.75 ± 774.67

3822.46 ± 905.39*

LVSP(mmHg)

120.99 ± 10.15

88.94 ± 6.86△△

95.70 ± 7.57*

105.24 ± 9.85**

LVEDP(mmHg)

−4.57 ± 1.71

5.72 ± 1.44△△

2.69 ± 0.88**

−0.98 ± 1.70**

  1. Values are expressed as the mean ± S.D. (n = 8 for Sham group and n = 12 for other groups). HR heart rate, SBP systolic blood pressure, DBP diastolic pressure, ±LV dp/dt max the maximal rates of increase and decrease of left ventricle pressure development, LVSP left ventricular systolic pressure, LVEDP left ventrilcel end dilated pressure. △△ P < 0.01 vs sham group; *P < 0.05, **P < 0.01 vs MI group
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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