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Table 4 Effect of 80 % methanol crude extracts of medicinal plants on body weight of P. berghei infected Swiss albino mice

From: Evaluation of the antiplasmodial properties of selected plants in southern Ethiopia

Medicinal plant

Dose mg/kg/day

Body weight (M ± SEM)

% of change (M ± SEM)

P value

Pre (D0)

Post (D4)

A. integrifolia

200

29.52 ± 0.29

31.30 ± 0.44

6.01 ± 0.51*a

0.000

400

27.60 ± 0.14

29.08 ± 0.32

8.56 ± 0.83*a

0.000

800

26.86 ± 0.28

29.76 ± 0.51

10.58 ± 0.68*a

0.000

C. myricoides

200

26.06 ± 0.21

27.34 ± 0.12

4.18 ± 0.60*a

0.006

400

28.82 ± 0.28

30.20 ± 0.14

5.84 ± 0.75*a

0.000

800

25.94 ± 0.15

27.98 ± 0.23

7.55 ± 0.67*a

0.000

M. azedarach

200

25.56 ± 0.11

26.70 ± 0.09

4.49 ± 0.38*a

0.000

400

26.78 ± 0.18

28.52 ± 0.30

6.56 ± 0.63*a

0.000

800

28.98 ± 0.26

31.32 ± 0.59

8.78 ± 0.89*a

0.000

P. vogelii

200

26.64 ± 0.18

27.52 ± 0.23

2.29 ± 0.39

0.062

400

28.60 ± 0.31

29.88 ± 0.30

4.48 ± 0.32*a

0.037

800

28.18 ± 0.31

30.02 ± 0.54

6.52 ± 0.95*a

0.008

P. schimperi

200

26.70 ± 0.41

27.46 ± 0.48

2.1 ± 0.24

0.065

400

29.24 ± 0.25

30.14 ± 0.15

4.0 ± 0.31*a

0.031

800

29.38 ± 0.28

31.10 ± 0.33

5.4 ± 0.50*a

0.042

NC

0

25.56 ± 0.24

24.10 ± 0.36

−5.56 ± 0.72

 

PC

10

26.52 ± 0.50

29.56 ± 0.49

10.73 ± 0.50

  1. Values are expressed as M ± SEM; n = 5
  2. NC negative control (0.2 mL of dH2O), PC positive control (Chloroquine), D4 day four
  3. *P < 0.05
  4. acompared to negative control