Fig. 3From: Antioxidative phytochemicals from Rhododendron oldhamii Maxim. leaf extracts reduce serum uric acid levels in potassium oxonate-induced hyperuricemic miceThe pathological histology of the EtOAc fraction and its derived phytochemicals of R. oldhamii leaf extract in PO-induced hyperuricemic mice. The H&E staining showed that PO-induced kidney injury caused renal tubular epithelial nuclear condensation (karyopyknosis) in the cortex or the appearance of numerous hyaline casts in the medulla areas. The levels of renal tubular epithelial nuclear condensation or numerous hyaline casts were significantly reduced by benzbromarone, the EtOAc fraction, (2R, 3R)-astilbin, hyposide, guaijaverin, and quercitrin treatmentsBack to article page