Anti-hyperglycaemic effects of herbal porridge made of Scoparia dulcis leaf extract in diabetics – a randomized crossover clinical trial

Senadheera, Senadheera Pathirannehelage Anuruddhika Subhashinie; Ekanayake, Sagarika; Wanigatunge, Chandanie

doi:10.1186/s12906-015-0935-6

BMC Complementary Medicine and Therapies

Table 4 AST, ALT, ALP, creatinine, urea and CRP measurements of groups 1 and 2

From: Anti-hyperglycaemic effects of herbal porridge made of Scoparia dulcis leaf extract in diabetics – a randomized crossover clinical trial

	Study period 1		Study period 2
AST(IU/L)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	36.7 ± 4.7	37.0 ± 2.4	51.6 ± 5.6	41.4 ± 3.4
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	32.5 ± 2.6	40.3 ± 4.3	39.0 ± 2.2	47.5 ± 4.1
ALT(IU/L)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	43.3 ± 5.7	39.0 ± 3.7	55.5 ± 8.1	41.2 ± 8.9
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	37.0 ± 4.7	42.6 ± 3.8	44.5 ± 5.3	43.0 ± 5.5
ALP(IU/L)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	214 ± 19	231 ± 13^a	232 ± 13	233 ± 12
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	258 ± 14	329 ± 24^b	330 ± 24	281 ± 20^c
	Study period 1		Study period 2
Creatinine (mg/dL)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	0.85 ± 0.04	0.93 ± 0.06	1.00 ± 0.05	0.90 ± 0.05^a
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	0.75 ± 0.03	0.92 ± 0.03^b	0.91 ± 0.03	0.91 ± 0.03
Urea (mmol/L)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	4.2 ± 0.34	4.1 ± 0.55	5.5 ± 0.64	3.4 ± 0.28^a
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	4.5 ± 0.33	4.1 ± 0.24	4.2 ± 0.30	3.6 ± 0.18
CRP (mg/dL)	Test (mean ± SEM)		Control (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 1^a	3.3 ± 0.74	3.4 ± 0.79	3.8 ± 1.05	3.0 ± 0.58
	Control (mean ± SEM)		Test (mean ± SEM)
	0 week	12 weeks	14 weeks	26 weeks
Group 2^b	4.3 ± 1.03	5.1 ± 0.88	5.1 ± 0.88	6.0 ± 1.11

Week 0 and week 14 indicates the basal serum parameters as those values have been obtained prior to the intervention
^an = 16; ^bn = 19; SEM = standard error of mean; Superscripts indicate a significant difference in a parameter when compared to basal value within a study period (p < 0.05)

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