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Table 4 Effect of TVL on serum lipids and liver enzymes in rats

From: Antioxidant, antidiabetic and hypolipidemic effects of Tulbaghia violacea Harv. (wild garlic) rhizome methanolic extract in a diabetic rat model

Parameters

Experimental groups

    
 

NDC

DC

D + TVL 60

D + TVL 120

D + glibenclamide

Triglycerides (mg/dl)

92.00 ± 10.58

134.50 ± 7.09*

100.70 ± 6.94#

93.14 ± 10.00#

93.50 ± 7.99#

Total cholesterol (mg/dl)

73.00 ± 2.48

82.25 ± 1.80

74.80 ± 5.20#

73.17 ± 4.45#

67.67 ± 4.70#

HDL-cholesterol (mg/dl)

24.40 ± 1.29

19.25 ± 0.75*

26.00 ± 1.58#

26.80 ± 1.86#

20.33 ± 2.08

LDL-cholesterol (mg/dl)

30.30 ± 1.66

36.10 ± 3.17

28.00 ± 1.88

27.67 ± 2.84

28.47 ± 3.14

VLDL (mg/dl)

18.40 ± 1.64

26.90 ± 1.42*

20.13 ± 1.39#

18.63 ± 2.00#

18.70 ± 1.60#

ALT (U/l)

62.60 ± 4.40

120.80 ± 12.52***

78.50 ± 6.83*##

77.75 ± 3.97* ##

83.25 ± 3.82*#

AST (U/l)

76.25 ± 1.25

98.00 ± 2.30*

78.83 ± 2.32#

79.83 ± 2.46#

81.00 ± 2.58#

  1. Non-diabetic control (NDC) and diabetic control (DC); TVL 60 mg/kg.b.w., (D + TVL 60 mg/kg.b.w.TVL 120 mg/kg.b.w.(D + TVL 120) and glibenclamide 10 mg/kg.b.w.(D + glibenclamide). All data are expressed as mean ± SEM for 7 animals per group
  2. *Significantly different from non-diabetic control p < 0.05
  3. ***Significantly different from non-diabetic control p < 0.001
  4. #Significantly different from diabetic control p < 0.05
  5. ##Significantly different from diabetic control p < 0.01