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Table 2 Effect of TVL on pre-treated (baseline) and post-treated (week 7) bodyweights, relative organ weights and food and water intake in rats during the experimental period

From: Antioxidant, antidiabetic and hypolipidemic effects of Tulbaghia violacea Harv. (wild garlic) rhizome methanolic extract in a diabetic rat model

Parameters

Experimental groups

    
 

NDC

DC

D + TVL60

D + TVL120

D + glibenclamide

Body weight (g)

     

Pre-treated

334.40 ± 17.82

281.30 ± 9.07*

276.00 ± 10.54*

284.10 ± 6.38*

291.50 ± 15.20

Post-treated

411.00 ± 16.27a

287.60 ± 8.88***

295.20 ± 11.52***

312.90 ± 8.29a***

312.60 ± 12.71***

% HW

0.27 ± 0.022

0.35 ± 0.01***

0.32 ± 0.01#

0.30 ± 0.01#

0.32 ± 0.01#

% LKW.

0.25 ± 0.01

0.47 ± 0.01***

0.41 ± 0.01*** #

0.38 ± 0.02*** #

0.40 ± 0.01***#

% LLW

1.21 ± 0.09

1.75 ± 0.03***

1.65 ± 0.03***

1.57 ± 0.04** #

1.55 ± 0.06** #

Food intake (g/rat/day)

16.00 ± 1.47

37.00 ± 2.03**

34.75 ± 1.96**

30.00 ± 3.30*

36.67 ± 4.01**

Water intake (ml/rat/day)

18.00 ± 3.74

158.00 ± 5.83***

132.90 ± 7.78***#

111.70 ± 11.08***#

121.70 ± 7.03***#

  1. Non-diabetic control (NDC) and diabetic control (DC); TVL 60 mg/kg.b.w.(D + TVL 60); TVL 120 mg/kg.b.w. (D + TVL 120) and glibenclamide 10 mg/kg.b.w. (D + glibenclamide. All data are expressed as mean ± SEM for 7 animals per group
  2. aSignificantly different from pre-treated weight, p < 0.05
  3. *Significantly different from NDC, p < 0.05
  4. **Significantly different from NDC, p < 0.01
  5. ***Significantly different from NDC, p < 0.001
  6. #Significantly different from DC, p < 0.05