Skip to main content

Advertisement

Fig. 7 | BMC Complementary and Alternative Medicine

Fig. 7

From: Tuscan black kale sprout extract bioactivated with myrosinase: a novel natural product for neuroprotection by inflammatory and oxidative response during cerebral ischemia/reperfusion injury in rat

Fig. 7

Bioactive TBK-SE modulates nitrotyrosine expression. Nitrotyrosine was evaluated by immunohistochemical evaluation in brain sections after CIR induction. Brain sections obtained from CIR untreated rats exhibited positive staining for nitrotyrosine in cortex (a), hippocampus (b), brainstem (c) and cerebellum (d) of CIR rats, while rats treated with bioactive TBK-SE showed negative staining for nitrotyrosine in cortex (e), hippocampus (f), brainstem (g) and cerebellum (h). By western blot analysis nitrotyrosine expression was evaluated. It was found a significant increase in nytrotirosine expression in cerebellum samples collected 7 days after CIR-induction from untreated rats. Conversely, cerebellum levels of nytrotirosine were reduced by administration of bioactive TBK-SE (i). GAPDH was used as internal control. ***p < 0.05 vs CIR

Back to article page