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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Tuscan black kale sprout extract bioactivated with myrosinase: a novel natural product for neuroprotection by inflammatory and oxidative response during cerebral ischemia/reperfusion injury in rat

Fig. 3

Bioactive TBK-SE treatment modulates unbalance between Bax and Bcl-2. Bax was evaluated by immunohistochemical evaluation in brain sections after CIR induction. Brain sections obtained from CIR untreated rats exhibited positive staining for Bax in cortex (a), hippocampus (b), brainstem (c) and cerebellum (d) of CIR rats, while rats treated with bioactive TBK-SE showed negative staining for Bax in cortex (e), hippocampus (f), brainstem (g) and cerebellum (h). Panel I shows ratio between Bax and Bcl-2 in cerebellum tissues, showing an higher expression of Bax/Bcl-2 in CIR untreated rats, attenuated by administration of bioactive TBK-SE (i). GAPDH was used as internal control. **p < 0.05 vs CIR

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