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Table 2 The sickling inhibitory activities of Scoparia dulcis crude extracts and fractions

From: Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae)

Time of incubation (min) Percentage inhibition (%)
A* B** C D E F G H I
0 time before incubation 59.2 ± 0.12 79.0 ± 0.22 59.8 ± 1.04 58.2 ± 0.52 60.0 ± 1.34 36.4 ± 0.68 58.0 ± 0.81 30.6 ± 0.72 57.0 ± 0.50
30 50.2 ± 0.31 76.2 ± 0.05 48.0 ± 0.08 55.2 ± 1.17 60.0 ± 0.66 29.0 ± 1.87 58.2 ± 0.86 35.2 ± 1.20 58.0 ± 1.92
60 49.0 ± 0.64 77.0 ± 1.31 54.2 ± 0.12 57.0 ± 0.82 66.2 ± 1.24 28.0 ± 0.66 59.0 ± 1.34 30.2 ± 1.35 56.0 ± 0.04
90 43.4 ± 0.27 73.0 ± 0.67 49.4 ± 1.65 55.4 ± 0.29 69.0 ± 0.95 20.2 ± 1.52 60.6 ± 1.10 31.2 ± 0.07 50.4 ± 1.66
120 43.2 ± 0.32 76.0 ± 0.04 59.0 ± 1.04 60.0 ± 1.06 75.2 ± 0.73 29.8 ± 1.34 58.0 ± 0.26 28.0 ± 1.32 45.4 ± 0.47
150 40.4 ± 0.41 69.2 ± 1.18 50.6 ± 0.06 52.0 ± 1.44 55.0 ± 1.42 28.0 ± 0.56 48.0 ± 1.05 20.0 ± 0.45 43.0 ± 1.40
180 39.0 ± 0.52 65.4 ± 1.06 50.0 ± 0.82 50.2 ± 0.85 52.4 ± 0.54 25.2 ± 1.47 45.0 ± 1.12 21.4 ± 0.73 43.0 ± 1.33
  1. Key:
  2. A = blood + Normal saline + Sodium metabisulphite
  3. B = blood + PHBA + Sodium metabisulphite
  4. C = blood + Crude extract of S. dulcis leaf at 100 mg/ml + Sodium metabisulphite
  5. D = blood + Crude extract of S. dulcis leaf at 300 mg/ml + Sodium metabisulphite
  6. E = blood + Crude extract of S. dulcis leaf at 500 mg/ml + Sodium metabisulphite
  7. F = blood + Petroleum ether fraction + Sodium metabisulphite
  8. G = blood + Chloroform fraction + Sodium metabisulphite
  9. H = blood + N-butanol fraction + Sodium metabisulphite
  10. I = blood + Aqueous fraction + Sodium metabisulphite
  11. Percentage sickling inhibitions of the aqueous methanol extracts of S. dulcis were significant all through the period of assay P < 0. 05 compared to normal saline*, but not with PHBA**