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Table 2 The sickling inhibitory activities of Scoparia dulcis crude extracts and fractions

From: Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae)

Time of incubation (min)

Percentage inhibition (%)

A*

B**

C

D

E

F

G

H

I

0 time before incubation

59.2 ± 0.12

79.0 ± 0.22

59.8 ± 1.04

58.2 ± 0.52

60.0 ± 1.34

36.4 ± 0.68

58.0 ± 0.81

30.6 ± 0.72

57.0 ± 0.50

30

50.2 ± 0.31

76.2 ± 0.05

48.0 ± 0.08

55.2 ± 1.17

60.0 ± 0.66

29.0 ± 1.87

58.2 ± 0.86

35.2 ± 1.20

58.0 ± 1.92

60

49.0 ± 0.64

77.0 ± 1.31

54.2 ± 0.12

57.0 ± 0.82

66.2 ± 1.24

28.0 ± 0.66

59.0 ± 1.34

30.2 ± 1.35

56.0 ± 0.04

90

43.4 ± 0.27

73.0 ± 0.67

49.4 ± 1.65

55.4 ± 0.29

69.0 ± 0.95

20.2 ± 1.52

60.6 ± 1.10

31.2 ± 0.07

50.4 ± 1.66

120

43.2 ± 0.32

76.0 ± 0.04

59.0 ± 1.04

60.0 ± 1.06

75.2 ± 0.73

29.8 ± 1.34

58.0 ± 0.26

28.0 ± 1.32

45.4 ± 0.47

150

40.4 ± 0.41

69.2 ± 1.18

50.6 ± 0.06

52.0 ± 1.44

55.0 ± 1.42

28.0 ± 0.56

48.0 ± 1.05

20.0 ± 0.45

43.0 ± 1.40

180

39.0 ± 0.52

65.4 ± 1.06

50.0 ± 0.82

50.2 ± 0.85

52.4 ± 0.54

25.2 ± 1.47

45.0 ± 1.12

21.4 ± 0.73

43.0 ± 1.33

  1. Key:
  2. A = blood + Normal saline + Sodium metabisulphite
  3. B = blood + PHBA + Sodium metabisulphite
  4. C = blood + Crude extract of S. dulcis leaf at 100 mg/ml + Sodium metabisulphite
  5. D = blood + Crude extract of S. dulcis leaf at 300 mg/ml + Sodium metabisulphite
  6. E = blood + Crude extract of S. dulcis leaf at 500 mg/ml + Sodium metabisulphite
  7. F = blood + Petroleum ether fraction + Sodium metabisulphite
  8. G = blood + Chloroform fraction + Sodium metabisulphite
  9. H = blood + N-butanol fraction + Sodium metabisulphite
  10. I = blood + Aqueous fraction + Sodium metabisulphite
  11. Percentage sickling inhibitions of the aqueous methanol extracts of S. dulcis were significant all through the period of assay P < 0. 05 compared to normal saline*, but not with PHBA**