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Table 2 Effect of S. crispus on SOD and LDH activities and level of MDA in AOM induced rats

From: Evaluation of chemopreventive potential of Strobilanthes crispus against colon cancer formation in vitro and in vivo

Groups

SOD (U/mL)

MDA (μM)

LDH (U/L)

Normal

6.17 ± 1.17

3.94 ± 0.27

1373.67 ± 137.29

AOM

8.16 ± 1.82

9.98 ± 0.78

1823.50 ± 97.96

FU

3.99 ± 1.12

3.60 ± 0.12***

776.33 ± 47.32**

S. crispus 250 mg/kg

10.98 ± 0.34*

4.34 ± 0.67***

729.17 ± 85.94**

S. crispus 500 mg/kg

11.21 ± 0.63*

3.21 ± 0.46***

779.67 ± 121.08**

  1. All values are expressed as mean ± SEM. Significant difference at *p < 0.01, **p < 0.001, ***p < 0.0001 vs AOM group (ANOVA, Tukey’s). FU Fluorouracil, AOM azoxymethane, LDH lactate dehydrogenase, SOD superoxide dismutase, MDA malondialdehyde