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Table 2 Effect of S. crispus on SOD and LDH activities and level of MDA in AOM induced rats

From: Evaluation of chemopreventive potential of Strobilanthes crispus against colon cancer formation in vitro and in vivo

Groups SOD (U/mL) MDA (μM) LDH (U/L)
Normal 6.17 ± 1.17 3.94 ± 0.27 1373.67 ± 137.29
AOM 8.16 ± 1.82 9.98 ± 0.78 1823.50 ± 97.96
FU 3.99 ± 1.12 3.60 ± 0.12*** 776.33 ± 47.32**
S. crispus 250 mg/kg 10.98 ± 0.34* 4.34 ± 0.67*** 729.17 ± 85.94**
S. crispus 500 mg/kg 11.21 ± 0.63* 3.21 ± 0.46*** 779.67 ± 121.08**
  1. All values are expressed as mean ± SEM. Significant difference at *p < 0.01, **p < 0.001, ***p < 0.0001 vs AOM group (ANOVA, Tukey’s). FU Fluorouracil, AOM azoxymethane, LDH lactate dehydrogenase, SOD superoxide dismutase, MDA malondialdehyde