Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Table 4 Effects of the flavonoid-rich fraction (FRF) from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on gastric lesions induced by ischemia and reperfusion

Gastric lesion models	Treatment (p.o.)	Dose (mg/kg)	ALU (mm²)	Inhibition (%)
Ischemia and Reperfusion	Normal	-	-	-
	Saline	10	181 ± 26	0
	Sham	-	156 ± 29	14
	Sa-FRF	100	52 ± 15*	72
	Sb-FRF	100	41 ± 25*	76

ANOVA followed by Dunnett’s test.*p < 0.05, **p < 0.01. Data are presented as mean ± S.D (n = 5-7)

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