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Table 2 Effects of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on gastric lesions induced by ethanol in rats pretreated with NEM

From: Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Pretreatment

Treatment (p.o.)

Dose (mg/kg)

UI (mm)

Increase Lesion (%)

Saline

Saline

10

27 ± 8

-

NEM (10 mg/Kg)

Saline

10

76 ± 21**

181

NEM (10 mg/Kg)

Sa-FRF

100

53 ± 11**

96

NEM (10 mg/Kg)

Sa-FDF

100

56 ± 13**

107

Saline

Saline

10

27 ± 8

-

NEM (10 mg/Kg)

Saline

10

83 ± 14*

207

NEM (10 mg/Kg)

Sb-FRF

100

56 ± 11*

107

NEM (10 mg/Kg)

Sb-FDF

100

69 ± 17*

155

  1. ANOVA followed by Dunnett’s test.* p < 0.05, ** p < 0.01. Data are presented as mean ± S.D (n = 5-7)