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Table 2 Effects of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on gastric lesions induced by ethanol in rats pretreated with NEM

From: Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Pretreatment Treatment (p.o.) Dose (mg/kg) UI (mm) Increase Lesion (%)
Saline Saline 10 27 ± 8 -
NEM (10 mg/Kg) Saline 10 76 ± 21** 181
NEM (10 mg/Kg) Sa-FRF 100 53 ± 11** 96
NEM (10 mg/Kg) Sa-FDF 100 56 ± 13** 107
Saline Saline 10 27 ± 8 -
NEM (10 mg/Kg) Saline 10 83 ± 14* 207
NEM (10 mg/Kg) Sb-FRF 100 56 ± 11* 107
NEM (10 mg/Kg) Sb-FDF 100 69 ± 17* 155
  1. ANOVA followed by Dunnett’s test.* p < 0.05, ** p < 0.01. Data are presented as mean ± S.D (n = 5-7)