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Table 1 Effects of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus on healing in acetic acid-induced gastric lesion

From: Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus

Gastric lesion models Treatment (p.o.) Dose (mg/kg) ALU (mm2) Inhibition (%)
Acetic acid Saline - 75 ± 8,6 -
  Cimetidine 100 22 ± 2,5** 71
  Sa-FRF 100 42 ± 1,6* 44
  Sa-FDF 100 65 ± 7,0 13
  Sb-FRF 100 49 ± 4,3* 35
  Sb-FDF 100 67 ± 25 11
  1. ANOVA followed by Dunnett’s test.*p < 0.05, **p < 0.01. Data are presented as mean ± S.D (n = 5-7)