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Table 1 IC50 values of analogs against NCI-H322, A549 cancer lines

From: Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines

Entry Lung (NCI-H322) Lung (A549)
IC50 (μM)
Juglone 19.32 ± 0.83 16.70 ± 0.88
15a 8.90 ± 0.20 4.72 ± 0.20
15b 15.60 ± 0.83 12.86 ± 0.48
15c 10.96 ± 0.68 10.20 ± 0.43
16a 7.94 ± 0.34 4.67 ± 0.18
16b 17.22 ± 1.18 15.08 ± 0.92
16c 13.30 ± 0.87 12.95 ± 0.81
17a 29.08 ± 1.20 23.83 ± 1.54
17b 26.52 ± 1.20 20.28 ± 1.15
17c 32.88 ± 1.63 25.32 ± 1.77
18a 24.34 ± 1.28 20.55 ± 0.82
18b 21.82 ± 1.25 19.12 ± 0.89
18c 24.55 ± 1.54 20.26 ± 0.72
19a 18.98 ± 0.99 15.12 ± 0.47
20a 18.28 ± 0.96 12.88 ± 0.42
BEZ-235 9.80 ± 0.25 6.28 ± 0.28
  1. BEZ-235 was used as positive control