Protective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats

Table 1 Initial body weight, final body weight, body weight gain, liver index and spleen index in differente experimental groups

Groups	Body weight (g)		Body weight gain (g)	Liver index (%)	Spleen index (%)
Groups	Initial	Final	Body weight gain (g)	Liver index (%)	Spleen index (%)
Sham	180.41 ± 14.31	321.50 ± 18.49	141.09 ± 12.72	2.75 ± 0.42	0.25 ± 0.035
CCl₄	179.66 ± 10.10	272.40 ± 21.03	92.74 ± 18.61*	5.97 ± 0.49^*	0.50 ± 0.055^*
CCl₄ + EPP	180.82 ± 9.28	308.22 ± 19.44	128.30 ± 24.50^#	3.58 ± 0.63^#	0.36 ± 0.055^#
CCl₄ + EPS	184.00 ± 10.98	309.10 ± 20.72	125.10 ± 22.09^#	3.55 ± 0.55^#	0.35 ± 0.039^#

EPP (150 mg/kg) and EPS (100 mg/kg) were administered orally for 4 weeks. The values are expressed as the mean ± S.D. (n = 10).*P < 0.05, compared with the sham group, ^#P < 0.05, compared with the CCl₄ group

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