Fig. 5From: Bixa orellana leaf extract suppresses histamine-induced endothelial hyperpermeability via the PLC-NO-cGMP signaling cascadeEffect of AEBO on histamine-induced cGMP production in cultured HUVEC. Three independent experiments were performed in triplicate. Data were expressed in mean ± SEM. Data were analyzed by One-way ANOVA. *P < 0.05 significant different from negative control. (B = basal level; N = Treated with histamine only; P = Drug control, 10 μM of LY 83583)Back to article page