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Table 4 Effect of ethanolic extract of c. roseus on blood sugar at different time intervals in steptozotocin-induced diabetic rats

From: Anti-diabetic potential of Catharanthus roseus Linn. and its effect on the glucose transport gene (GLUT-2 and GLUT-4) in streptozotocin induced diabetic wistar rats

Groups Blood glucose (mg/dl)
Before treatment After treatment
  8th day 11th day 14th day 17th day 20th day 23th day 26th day 28th day
Normal Control Group 113 ± 3.5 107 ± 3.4 109 ± 3.9 115 ± 4.2 112 ± 4.3 108 ± 3.3 109 ± 2.9 105 ± 3.3 110 ± 2.9
Diabetic Group 112 ± 4.4 248 ± 3.8 281 ± 3.1 299 ± 3.9 314 ± 3.1 329 ± 3.6 343 ± 3.5 373 ± 3.1 398 ± 3.4
Treated with 100 mg/kg c. roseus 118 ± 4.8 254 ± 3.1 242 ± 4.3 235 ± 4.7 224 ± 4.0 212 ± 3.7 195 ± 4.3 180 ± 4.1 138 ± 4.8
Treated with 200 mg/kg c. roseus 114 ± 3.9 269 ± 3.9 232 ± 4.1 223 ± 3.6 218 ± 4.4 205 ± 4.7 190 ± 3.3 169 ± 4.5 123 ± 4.1
Treated with 100 mg/kg Metformin 117 ± 4.1 247 ± 3.2 243 ± 3.6 238 ± 3.1 225 ± 3.6 214 ± 3.6 201 ± 3.9 188 ± 3.6 141 ± 3.5