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Table 4 Effect of crude methanolic extract of the seeds of B. nigra on the body weights of P. berghei infected mice in suppressive test

From: Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Treatments

Doses

Body Weight (gm)

D0-Weight

D4-Weight

Wt Change (%)

Distilled water

10 ml/kg

29.64 ± 0.34

29.30 ± 0.32

−1.15

Brassica nigra seed extract

100 mg/kg

30.38 ± 1.89

30.48 ± 2.05

0.33

200 mg/kg

26.68 ± 1.57

26.92 ± 1.57

0.90a1

400 mg/kg

29.26 ± 1.41

29.62 ± 1.42

1.23a1

Chloroquine

10 mg/kg

28.18 ± 1.64

28.58 ± 1.65

1.42a2

  1. Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; 1 = P < 0.01 and 2 = P < 0.001
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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