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Table 4 Effect of crude methanolic extract of the seeds of B. nigra on the body weights of P. berghei infected mice in suppressive test

From: Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Treatments Doses Body Weight (gm)
D0-Weight D4-Weight Wt Change (%)
Distilled water 10 ml/kg 29.64 ± 0.34 29.30 ± 0.32 −1.15
Brassica nigra seed extract 100 mg/kg 30.38 ± 1.89 30.48 ± 2.05 0.33
200 mg/kg 26.68 ± 1.57 26.92 ± 1.57 0.90a1
400 mg/kg 29.26 ± 1.41 29.62 ± 1.42 1.23a1
Chloroquine 10 mg/kg 28.18 ± 1.64 28.58 ± 1.65 1.42a2
  1. Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; 1 = P < 0.01 and 2 = P < 0.001