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Table 3 Effect of crude methanolic extract of the seeds of B. nigra on the mean survival times of P. berghei infected mice in both suppressive and prophylactic tests

From: Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Tests

Treatments

Doses

Mean Survival Times (Days)

Suppressive

Distilled water

10 ml/kg

7.20 ± 0.37

Brassica nigra seed extract

100 mg/kg

7.60 ± 0.25b2

200 mg/kg

9.00 ± 0.45a1,b2

400 mg/kg

9.00 ± 0.71a1,b2

Chloroquine

10 mg/kg

15.00 ± 0.00a2

Prophylactic

Distilled water

10 ml/kg

6.80 ± 0.20

Brassica nigra seed extract

100 mg/kg

7.00 ± 0.32b2

200 mg/kg

7.60 ± 0.25b2

400 mg/kg

7.80 ± 0.37b2

Chloroquine

10 mg/kg

14.60 ± 0.40a2

  1. Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; b = as compared to positive control; 1 = P < 0.05 and 2 = P < 0.001