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Table 3 Effect of crude methanolic extract of the seeds of B. nigra on the mean survival times of P. berghei infected mice in both suppressive and prophylactic tests

From: Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Tests Treatments Doses Mean Survival Times (Days)
Suppressive Distilled water 10 ml/kg 7.20 ± 0.37
Brassica nigra seed extract 100 mg/kg 7.60 ± 0.25b2
200 mg/kg 9.00 ± 0.45a1,b2
400 mg/kg 9.00 ± 0.71a1,b2
Chloroquine 10 mg/kg 15.00 ± 0.00a2
Prophylactic Distilled water 10 ml/kg 6.80 ± 0.20
Brassica nigra seed extract 100 mg/kg 7.00 ± 0.32b2
200 mg/kg 7.60 ± 0.25b2
400 mg/kg 7.80 ± 0.37b2
Chloroquine 10 mg/kg 14.60 ± 0.40a2
  1. Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; b = as compared to positive control; 1 = P < 0.05 and 2 = P < 0.001