Antimalarial activity of 80 % methanolic extract of Brassica nigra (L.) Koch. (Brassicaceae) seeds against Plasmodium berghei infection in mice

Table 2 Chemoprophylactic activity of methanolic crude extract of the seeds of Brassica nigra against Plasmodium berghei infection in mice

Treatments	Doses	% Parasitemia	% Chemosuppression
Distilled water	10 ml/kg	26.40 ± 5.80	0.00
Brassica nigra seed extract	100 mg/kg	21.80 ± 2.65	17.42^b2
	200 mg/kg	20.80 ± 3.01	21.21^b2
	400 mg/kg	12.20 ± 1.36	53.79^a1
Chloroquine	10 mg/kg	1.00 ± 0.45	96.21^a3

Values are expressed as Mean ± SEM; n = 5. Where a = as compared to negative control; b = as compared to positive control; 1 = P < 0.05; 2 = P < 0.01 and 3 = P < 0.001

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