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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: XingNaoJing, prescription of traditional Chinese medicine, prevents autophagy in experimental stroke by repressing p53-DRAM pathway

Fig. 5

p53 is responsible for the effects of XNJ on preventing autophagy. a Suppression of p53 by p53 inhibitor significantly reduced the effects of XNJ on the autophagy. PC12 cells were cultured in serum-free condition and stimulated with p53 inhibitor in the absence or presence of XNJ, the expression levels of LC3 and p62 were analyzed using Western blot assay. b Comparison of the density of LC3-II/β-actin band among the experimental groups was showed. c Comparison of the density of p62/β-actin band among the experimental groups was exhibited. *, p < 0.05 compared with the serum-free condition group

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