Studies on phytochemical, antioxidant, anti-inflammatory and analgesic activities of Euphorbia dracunculoides

Table 7 Effect of E. dracunculoides on carrageenan-induced paw edema in rat

Treatment mg/kg	Edema volume (ml)/ Percent edema inhibition
Treatment mg/kg	0 h	1 h	2 h	3 h	4 h
DMSO (2 ml)	0.506 ± 0.046	0.776 ± 0.045	0.710 ± 0.021	0.671 ± 0.017	0.600 ± 0.021
DIC (10)	0.551 ± 0.056	0.706 ± 0.056	0.640 ± 0.049	0.613 ± 0.049	0.586 ± 0.056
DIC (10)	0.551 ± 0.056	42.862 ± 5.614^ab	56.903 ± 8.443^ab	69.975 ± 5.730^a	78.823 ± 6.395^a
EDH (300)	0.548 ± 0.022	0.685 ± 0.033	0.630 ± 0.021	0.615 ± 0.018	0.600 ± 0.023
EDH (300)	0.548 ± 0.022	49.652 ± 7.649^a	60.171 ± 3.690^a	67.524 ± 8.004^a	68.660 ± 10.502^a
EDA (300)	0.548 ± 0.035	0.751 ± 0.027	0.696 ± 0.030	0.683 ± 0.032	0.651 ± 0.031
EDA (300)	0.548 ± 0.035	24.960 ± 7.283^c	27.492 ± 5.730^d	34.028 ± 9.170^c	37.156 ± 6.297^c
EDE (300)	0.560 ± 0.037	0.730 ± 0.016	0.676 ± 0.037	0.651 ± 0.039	0.640 ± 0.026
EDE (300)	0.560 ± 0.037	37.307 ± 8.113^abc	43.014 ± 12.271^bc	55.269 ± 7.215^ab	51.384 ± 8.623^b
EDEW (300)	0.520 ± 0.046	0.705 ± 0.045	0.643 ± 0.030	0.633 ± 0.044	0.608 ± 0.039
EDEW (300)	0.520 ± 0.046	31.752 ± 3.883^bc	39.746 ± 10.125^cd	44.648 ± 9.127^bc	46.302 ± 8.975^bc
EDM (300)	0.545 ± 0.032	0.738 ± 0.026	0.683 ± 0.031	0.676 ± 0.026	0.653 ± 0.039
EDM (300)	0.545 ± 0.032	28.665 ± 11.396^c	32.394 ± 8.443^cd	35.662 ± 12.938^c	34.107 ± 8.975^c

EDH E. dracunculoides n-hexane extract, EDA E. dracunculoides aqueous extract, EDE E. dracunculoides ethyl acetate, EDEW E. dracunculoides ethyl acetate + water extract, EDM E. dracunculoides methanol extract (EDM), DIC diclofenac sodium
Data values shown represent mean ± SD (n = 6). Means with different superscript (^a-d) letters in the column are significantly (P < 0.05) different from one another

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