Table 4 Change in drug prescriptions and cost of drugs during 180 days before/after first observed inpatient visit with diagnosis F43 for the integrative care and conventional care cohorts
Integrative Care (N=161) | Conventional Care (N=1571) | Conventional-Integrative | Conventional-Integrative | |
|---|---|---|---|---|
Change from 180-days before to 180-days after index visit | Difference in change between groups | Effect size (Cohen’s d) | ||
DDDs/patient | ||||
ATC-N05A | −0.2 (−1.6 to 1.2), p = 0.767 | 2.0 (0.5 to 3.5), p = 0.004 | 2.2 (−2.4 to 6.8), p = 0.351 | 0.1 (−0.1 to 0.2) |
ATC-N05B | −15.3 (−26.7 to −3.8), p = 0.004 | 27.2 (20.3 to 34.1), p < 0.001 | 42.5 (20.6 to 64.4), p < 0.001 | 0.3 (0.2 to 0.5) |
ATC-N05C | −3.8 (−6.4 to −1.2), p = 0.002 | 12.3 (10.1 to 14.5), p < 0.001 | 16.1 (9.2 to 22.9), p < 0.001 | 0.4 (0.2 to 0.5) |
ATC-N06A | −7.4 (−18.4 to 3.5), p = 0.091 | 22.5 (17.4 to 27.5), p < 0.001 | 29.9 (13.7 to 46.1), p < 0.001 | 0.3 (0.1 to 0.5) |
Cost/patient (EUR) | ||||
ATC-N05A | 12.8 (−13.9 to 39.5), p = 0.345 | 25.7 (14.8 to 36.5), p < 0.001 | 12.9 (−22.1 to 47.8), p = 0.471 | 0.1 (−0.1 to 0.2) |
ATC-N05B | −2.8 (−4.7 to −0.8), p = 0.003 | 4.5 (3.0 to 6.0), p < 0.001 | 7.2 (2.5 to 12.0), p = 0.003 | 0.3 (0.1 to 0.4) |
ATC-N05C | −2.7 (−4.6 to −0.9), p = 0.002 | 5.4 (3.9 to 6.9), p < 0.001 | 8.1 (3.5 to 12.7), p < 0.001 | 0.3 (0.1 to 0.5) |
ATC-N06A | −12.6 (−31.1 to 5.9), p = 0.181 | 27.9 (21.3 to 34.6), p < 0.001 | 40.5 (18.9 to 62.1), p < 0.001 | 0.3 (0.1 to 0.5) |