Skip to main content

Advertisement

Table 2 Effect of the methanolic fraction from Clerodendrum umbellatum leaves aqueous extract on the liver and spleen weights of mice on the 65th day post-infection

From: Schistosomicidal, hepatoprotective and antioxidant activities of the methanolic fraction from Clerodendrum umbellatum Poir leaves aqueous extract in Schistosoma mansoni infection in mice

Groups Number of animals (n) Liver Spleen
Weight (g/100 g) p % change Weight (g/100 g) p % change
NIC 5 6.23 ± 0.34    0.50 ± 0.04   
IC 6 9.21 ± 0.37 <0.001 +47.83 1.45 ± 0.17 <0.001 +190.00
PZQ 6 6.57 ± 0.46 <0.001 −28.66 0.43 ± 0.08 <0.001 −70.34
CuF100 6 7.68 ± 0.28 <0.05 −16.61 0.77 ± 0.08 <0.001 −46.90
CuF200 6 7.90 ± 0.48 <0.05 −14.22 0.79 ± 0.03 <0.001 −45.52
CuF400 6 5.96 ± 0.47 <0.001 −35.29 0.66 ± 0.10 <0.001 −54.48
  1. Data are expressed as mean ± SEM
  2. ANOVA followed by Newman-Keuls multiple comparison test was used to compare on one hand, the infected-untreated mice (IC) to the non-infected mice (NIC), and secondly the infected-treated mice (PZQ, CuF100, CuF200, CuF400) to the infected-untreated mice (IC)