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Table 1 Effect of the methanolic fraction from Clerodendrum umbellatum leaves aqueous extract on the body weight of mice at pre-infection and on the 65th day post-infection

From: Schistosomicidal, hepatoprotective and antioxidant activities of the methanolic fraction from Clerodendrum umbellatum Poir leaves aqueous extract in Schistosoma mansoni infection in mice

Groups Number of animals (n) Body weight (g) Weight gain (%) p
Pre-infection (1st day) Post-infection (65th day)
NIC 5 19.30 ± 0.83 24.23 ± 1.05 29.53 ± 2.04 (24.28–34.78)  
IC 6 23.51 ± 0.90 24.31 ± 0.80 3.97 ± 3.87 (−5.50–13.44) <0.001
PZQ 6 21.22 ± 1.04 26.00 ± 0.98 22.89 ± 2.89 (15.47–30.31) <0.001
CuF100 6 23.55 ± 0.55 28.14 ± 0.85 19.54 ± 2.56 (12.95–26.12) <0.01
CuF200 6 21.04 ± 0.89 24.94 ± 1.03 18.60 ± 1.43 (14.93–22.26) <0.001
CuF400 6 22.74 ± 0.51 27.07 ± 0.74 19.06 ± 1.96 (14.03–24.09) <0.001
  1. Data are expressed as mean ± SEM
  2. Values in brackets represent the 95 % confidence intervals
  3. ANOVA followed by Newman-Keuls multiple comparison test was used to compare on one hand, the infected-untreated mice (IC) to the non-infected mice (NIC), and secondly the infected-treated mice (PZQ, CuF100, CuF200, CuF400) to the infected-untreated mice (IC)