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Table 5 Subchronic effect of F.hermonis EtAc extract (Ferula), Ferutinin (Ft) on body weights in alloxan-induced diabetic mice (n = 7)

From: Acute and subchronic in-vivo effects of Ferula hermonis L. and Sambucus nigra L. and their potential active isolates in a diabetic mouse model of neuropathic pain

Group

Dose (mg/kg)

Mean body weight ± S.E.M. (gm)

  

1st day

3rd day

5th day

8th day

Control

__

25.90 ± 0.50

26.00 ± 0.60

26.01 ± 0.97

25.09 ± 0.70

Diabetic controla

__

28.68 ± 0.70

27.10 ± 0.20

27.15 ± 0.80

27.10 ± 0.50

GBb

5

22.90 ± 0.70

28.17 ± 1.70

28.54 ± 0.40

30.37 ± 1.10*

Ferula b

12.5

26.00 ± 1.30

26.60 ± 1.70

26.70 ± 2.00

26.70 ± 1.20*

Ferula b

25

27.20 ± 1.70

27.50 ± 1.80

27.50 ± 1.80

27.80 ± 2.20*

Ferula b

50

25.10 ± 1.50

27.20 ± 2.10

27.54 ± 1.90

28.50 ± 2.40*

Ftb

0.4

25.31 ± 1.80

26.80 ± 1.50

26.90 ± 1.60

27.10 ± 1.90*

Ftb

0.8

27.00 ± 1.70

28.10 ± 2.10

28.30 ± 1.30

28.33 ± 2.10*

Ftb

1.6

28.50 ± 1.90

29.60 ± 2.50

30.10 ± 2.40

31.80 ± 2.80*

  1. S.E.M. standard error of the mean
  2. *p < 0.05 significant from the control animals
  3. aCompared to vehicle control
  4. bCompared to diabetic control