Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stress

Table 5 Effect of turmeric on hepatic injuries

Groups	Degree of liver tissue injury	The Kruskal-Wallis tes
Control	0.0 ± 0.0	P < 0.001
TUR (100mgkg⁻¹)	0.0 ± 0.0
TUR (200mgkg⁻¹)	0.0 ± 0.0
MTX (20mgkg⁻¹)	2.83 ± 0.78^a
TUR (100mgkg⁻¹) + MTX	2.20 ± 0.61^a
TUR (200mgkg⁻¹) + MTX	0.45 ± 0.18^b

Values are shown as mean ± S.D.
TUR Turmeric, MTX Methotrexate
0 = without injury, 1 = minimum injury, 2 = mild injury, 3 = moderate injury, 4 = sever injury. ^aSignificant different with control group at P < 0.05. ^bSignificant different with MTX at P < 0.05

ISSN: 2662-7671