Fig. 6From: Pre-administration of turmeric prevents methotrexate-induced liver toxicity and oxidative stressEffect of turmeric on PMN content of MTX-induced hepatic injuries. The number of neutrophils was obtained by counting these cells in 50 high-power fields. In control livers, relatively few neutrophils were found at sites of erosion. Similar results were obtained in group II and III. There was a significant increase in the number of neutrophils in the liver of rats treated with MTX (P < 0.05). There was no statistically significant difference between number of neutrophils in rats treated with MTX + turmeric (100 mg/kg) as compared to livers obtained from rats injected with MTX (group IV). However, the number of neutrophils accumulating in the liver in group (MTX + turmeric 200 mg/kg) has been significantly different compared to MTX treatment group (P < 0.05). Values are shown as mean ± S.D. * P < 0.05 compared with control, ** P < 0.05 compared with MTX groupBack to article page