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Table 2 Summary of the SNPs associated with high Yu-Zhi score in type 2 diabetes

From: Susceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine

      RA frequency      
dbSNP ID Chr. Position (Mb) Gene RA* (NRA) High YZ score Low YZ score p-value (Best model) -log (p-value) best model Effect size (95 % CI) FDR
rs12036718 1p 48.3 Unknow T(C) 0.174 0.103 8.10 × 10−6 5.09 Trend 1.68 (0.95 -2.99) 1.00
rs1932064 1p 70.8 Unknow T(C) 0.788 0.700 6.18 × 10−6 5.21 Dominant 1.62 (1.05 -2.51) 0.97
rs8179355 1p 70.9 Unknow C(A) 0.782 0.699 7.53 × 10−6 5.12 Recessive 1.54 (1.25 -1.89) 0.86
rs9633289 1p 70.9 Unknow T(A) 0.217 0.298 6.18 × 10−6 5.21 Recessive 1.55 (1.11 -2.15) 0.95
rs7565310 2q 128.9 Unknow A(G) 0.484 0.380 8.63 × 10−6 5.06 Trend 1.53 (1.27 -1.84) 0.83
rs7694118 4q 134.3 PCDH10 C(T) 0.698 0.663 6.31 × 10−6 5.20 Genotype 1.30 (0.85 -1.99) 1.00
rs164368 5q 160.6 Unknow T(C) 0.803 0.785 6.14 × 10−6 5.21 Genotype 1.12 (0.89 -1.40) 1.00
rs7493 7q 94.9 PON2 C(G) 0.180 0.177 5.33 × 10−6 5.27 Genotype 1.06 (0.74 -1.51) 1.00
rs2299263 7q 94.9 PON2 A(G) 0.180 0.177 5.33 × 10−6 5.27 Genotype 1.06 (0.74 -1.51) 1.00
rs17166875 7q 94.9 PON2 T(C) 0.180 0.177 5.33 × 10−6 5.27 Genotype 1.02 (0.81 -1.29) 1.00
rs12865228 13q 38.2 FREM2 G(T) 0.429 0.414 3.38 × 10−6 5.47 Genotype 1.06 (0.88 -1.28) 1.00
rs4526895 13q 38.2 FREM2 C(T) 0.428 0.414 1.79 × 10−6 5.75 Genotype 1.38 (0.93 -2.04) 1.00
rs17118382 14q 82.8 Unknow A(G) 0.815 0.730 9.75 × 10−6 5.01 Allele 1.45 (1.03 -2.04) 0.98
rs194045 16p 29.2 Unknow G(A) 0.943 0.888 6.31 × 10−6 5.20 Trend 2.13 (1.51 -3.02) 0.83
rs8093481 18p 10.7 PIEZO2 A(G) 0.757 0.656 9.64 × 10−7 6.02 Trend 1.79 (1.16 -2.77) 0.93
rs11660953 18p 10.7 PIEZO2 T(C) 0.756 0.656 1.60 × 10−6 5.79 Trend 1.79 (1.16 -2.77) 0.93
rs1133146 19q 58.4 ZNF665 A(G) 0.990 0.956 4.77 × 10−6 5.32 Allele 1.52 (1.01 -2.29) 0.99
rs12971799 19q 58.4 ZNF665 C(T) 0.700 0.599 4.77 × 10−6 5.32 Allele 1.49 (0.99 -2.25) 1.00
rs4801958 19q 58.4 ZNF665 T(C) 0.700 0.599 4.77 × 10−6 5.32 Allele 1.56 (1.29 -1.89) 0.83
rs12460170 19q 58.4 ZNF665 G(A) 0.699 0.600 7.56 × 10−6 5.12 Allele 1.56 (1.29 -1.89) 0.83
rs4803055 19q 58.4 ZNF665 C(T) 0.737 0.639 4.87 × 10−6 5.31 Allele 1.56 (1.02 -2.38) 0.98
rs871913 20p 16.1 Unknow A(G) 0.099 0.045 8.24 × 10−6 5.08 Trend 1.86 (0.78 -4.44) 1.00