Fig. 1

Unripe papaya pulp juice promotes gap closure in vitro SHED scratch culture. Addition of 10% UPJ significantly (p = .008) reduced scratch gap width (a) and gap area (b) compared with control groups. Addition of 2% and 5% UPJ did not show any significant difference. Representative photomicrographs of scratch assay of control and 10% UPJ groups at 0 hour (c and e respectively) and 24 hour (d and f respectively). Dotted lines (c and e) show initial scratch. In vitro addition of 2%, 5% and 10% UPJ did not significantly affect SHEDs’ viability (g). *Significantly higher than control group (p = .008); n = 9; [scale bar (C-F): 50 μm]