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Table 1 Effects of ethanol extract of mulberry on various biochemical parameters in rats with chemically induced liver toxicity

From: Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat

Groups

ALT activity (U/l)

AST activity (U/l)

ALP activity (U/l)

LDH activity U/l

Total protein g/dl

Albumin g/dl

Albumin to Globulin Ratio. (A/G) g/dl

Control

40.50 ± 3.28

93.25 ± 2.36

66.00 ± 7.12

470.50 ± 9.14

7.100 ± 0.163

4.13 ± 0.16

1.50 ± 0.04

MUL

19.50 ± 1.19

62.00 ± 5.79

36.25 ± 9.25

422.25 ± 12.25

7.00 ± 0.73

4.03 ± 0.06

1.43 ± 0.03

MTX-

71.00 ± 12.34a

135.75 ± 25.55a

110.25 ± 13.82a

1607.25 ± 121.57a

6.63 ± 0.10

3.83 ± 0.33

1.20 ± 0.08

MUL+ MTX

21.75 ± 3.25b

82.00 ± 6.00b

99.00 ± 7.55b

393.00 ± 87.18b

6.93 ± 0.048

3.70 ± 0.29

1.35 ± 0.23

  1. Values are expressed as mean ± S.E. for five rats in each group
  2. aSignificantly different from control using one way ANOVA followed by Duncan
  3. bSignificantly different compared with MTX-treated group using one way ANOVA followed by Duncan