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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Paecilomycies japonica reduces repeated nicotine-induced neuronal and behavioral activation in rats

Fig. 1

Effects of PJ on nicotine-induced locomotor sensitization. Rats were pretreated with vehicle (▲), PJ (10 mg/kg, i.p., PJ10(dev)), PJ (25 mg/kg, i.p., PJ25(dev)), PJ (50 mg/kg, i.p., PJ50(dev)), PJ (100 mg/kg, i.p., □ PJ100(dev)), or PJ (200 mg/kg, i.p., PJ200(dev)) 30 min before injections of nicotine twice daily for 7 consecutive days. The saline-treated group was treated with only saline (■). * = significant difference from saline-treated, nicotine-treated group and # from saline or PJ-pretreated and nicotine-treated group: *, P < 0.05; **, P < 0.01; ***, P < 0.001; #, P < 0.05; ##, P < 0.01; ###, P < 0.001. Vertical lines indicate S.E.M. (N = 6–7)

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