Fig. 2

Effect of Haelan on the proliferation of pancreatic carcinoma cells and fibroblasts. CAPAN-1 cells (a), BxPC-3 cells (b), AR42J cells (c) and fibroblasts (d) were incubated with or without increasing concentrations of Haelan. After 24 h, the proliferation was measured using the WST-1 assay. Haelan exerts significant effects on cell proliferation dependent upon cell type and concentration. The concentration of 8 % Haelan induces growth arrest in all pancreatic cancer cells, but not in the fibroblasts. The results are expressed as mean + SEM (n = 3-12). *P < 0.05, ***P < 0.001, control vs. Haelan-treated cells