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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: Water extract of brewers’ rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers’ rice-treated rats with azoxymethane-induced colon carcinogenesis

Fig. 5

Immunohistochemical staining of cyclin D1. The expression of cyclin D1 in three sections, including distal, middle, and proximal colon in normal (Group 1), AOM alone (untreated) (Group 2) compared to groups of rats treated with 10 % (Group 3), 20 % (Group 4), and 40 % (Group 5) (w/w) of brewers’ rice (n = 3). Expression of cyclin D1 showed cytoplasm and nucleus staining: strong cyclin D1 in Group 2, weaker staining of cyclin D1 in Group 3 and Group 4, and the weakest staining of cyclin D1 in Group 5 (Magnification 200×). Scale bars in the figures indicate 100 μm

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