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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Water extract of brewers’ rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers’ rice-treated rats with azoxymethane-induced colon carcinogenesis

Fig. 2

mRNA levels of HT-29 cells treated with WBR. Expression of aAXIN1, b casein kinase 1 (CK1), c glycogen synthase kinase 3β (GSK3β), and d adenomatous polyposis coli (APC) in Wnt signaling at mRNA levels in HT-29 cells incubated with WBR (n = 3). Value with different superscript letter indicates significant difference between groups by Tukey’s test (P < 0.05). AXIN1 gene did not significantly differ between the control cells and those from the groups treated with 32 or 64 μg/mL WBR (P > 0.05). CK1 mRNA level in the groups treated with 32 and 64 μg/mL WBR was significantly increased compared with the control (P < 0.05). GSK3β mRNA level in the group treated with 64 μg/mL WBR was significant decreased compared with the control (P < 0.05). APC gene in the groups treated with WBR was significantly elevated compared with the control (P < 0.05)

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