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Table 1 Activities of amylase, lipase, alanine transaminase (ALT), aspartate transaminase (AST), and interleukin-6 (IL-6) levels in serum samples

From: Suppression of acute pancreatitis by L-lysine in mice

Group:

I

II

III

IV

Parameter

(Normal)

(Arginine, 400 mg/kg)

(Arginine + Lysine) treated

(Arginine + Lysine) protected

Amylase (U/l)

    

Mean ± SD

400 ± 45

1600 ± 99

1191 ± 84

650 ± 75

P value

---

<0.001

<0.001

<0.001

P*

 

---

<0.001

<0.001

Lipase (U/l)

    

Mean ± SD

127 ± 19

397 ± 76

211 ± 57

180 ± 79

P value

---

<0.001

<0.001

<0.001

P*

 

--

<0.01

<0.01

AST(U/l)

    

Mean ± SD

25 ± 2.3

64 ± 2.0

46 ± 2.5

33 ± 9

P value

 

<0.001

<0.001

<0.001

P*

  

<0.05

<0.05

ALT(U/l)

    

Mean ± SD

24 ± 3.1

50.7 ± 4.2

42 ± 2.2

36 ± 2.6

P value

---

<0.001

<0.001

<0.001

P*

 

--

<0.05

<0.001

IL-6 (ng/l)

    

Mean ± SD

22 ± 2.1

90.7 ± 7.7

63 ± 5.1

39 ± 5

P value

---

<0.05

<0.05

<0.001

P*

 

--

<0.05

<0.01

  1. P < 0.05 compared with the control
  2. * Treated versus untreated