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Table 2 DRD2 TaqIA genotypic distribution and allelic frequencies

From: Association between the traditional Chinese medicine pathological factors of opioid addiction and DRD2/ANKK1 TaqIA polymorphisms

  Genotypic Distribution (%) Allele Frequency (%)  
Group A1A1 A1A2 A2A2 A1 A2 HWEP-value
Full (n = 502) 71 (14.1) 252 (50.2) 179 (35.7) 394 (39.2) 610 (60.8) 0.238
Males (n = 289) 39 (13.5) 137 (47.4) 113 (39.1) 215 (37.2) 363 (62.8)  
Females (n = 213) 32 (15.0) 115 (54.0) 66 (31.0) 179 (42.0) 247 (58.0)  
Opioid addicts (n = 347) 50 (14.4) 168 (48.4) 129 (37.2) 268 (38.6) 426 (61.4) 0.692
Health group (n = 155) 21 (13.5) 84 (54.2) 50 (32.3) 126 (40.6) 184 (59.4) 0.125
Addiction intensity = 1 26 (7.49) 88 (23.4) 58 (16.7) 140 (20.2) 204 (29.4)  
Addiction intensity = 2 24 (6.91) 81 (23.3) 70 (20.2) 129 (18.6) 221 (31.8)  
  1. Genotype comparison between males and females: χ2 = 3.53, df = 2, p = 0.171
  2. Genotype comparison between opioid addicts and health group: χ2 = 1.034, df = 2, p = 0.596
  3. Genotype comparison between different addiction intensities: χ2 = 1.469, df = 2, p = 0.480
  4. Full: includes both males and females
  5. Hardy-Weinberg equilibrium of genotype distributions of each polymorphism was tested for all of the participants, opioid addicts, and health group