Fig. 3From: The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cellsEffect of EGCG on caspase activity and cell cycle in TFK-1 cells. a Time-dependent effect of 50 μM EGCG on caspase activity in TFK-1 cells. For each time point, values are related to untreated control. b Cell cycle distribution of TFK-1 cells after 72 h. Sub-G1 represents cells with a DNA content less than 2 N, G0/G1 cells with DNA content 2 N, S cells with DNA content greater than 2 N and G2/M cells with DNA content 4 N. c Representative microscopic pictures of EGCG-treated and untreated TFK-1 cells, showing cell shrinkage, rounding and apoptotic bodies, respectively. Abbreviations: EGCG: Epigallocatechin gallateBack to article page