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Table 1 Levels of independent variables for reflux extraction condition based on CCD

From: Optimization protocol for the extraction of 6-gingerol and 6-shogaol from Zingiber officinale var. rubrum Theilade and improving antioxidant and anticancer activity using response surface methodology

  Coded
Variable −1 0 1 Axial (−α) Axial (+α)
X1: extraction temperature 50 65 80 47.1 82.8
X2: extraction time 2 3 4 1.8 4.1