Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Table 4 Effects of aqueous and methanol extracts of P. africanum on nitric oxide dosage

Treatment	Dose (mg/kg)	n	[NO] Plasma (μmol/ml)	[NO] Gastric supernatant (μmol/g)
Normal	/	6	3.09 ± 0.24	9.18 ± 0.71*
Distilled water	/	6	2.60 ± 0.22	12.96 ± 0.26
Maalox	50	6	3.40 ± 0.34	13.68 ± 0.67
Ranitidine	50	6	3.21 ± 0.33	7.66 ± 0.40**
Aqueous extract of P. africanum	125	6	1.64 ± 0.22*	16.91 ± 1.59**
	250	6	2.10 ± 0.22	13.78 ± 0.65
	500	6	2.71 ± 0.10	16.03 ± 0.76
Methanol extract of P. africanum	125	6	2.51 ± 0.17	15.23 ± 0.74
	250	6	7.30 ± 0.51**	11.17 ± 0.42
	500	6	4.65 ± 0.50**	13.88 ± 0.95

n = number of animals per group, [NO] = Nitric oxide concentration, *Significant difference at 0,05 in relation to the control group having received distilled water, **Significant difference at 0,01 in relation to the control group having received distilled water

ISSN: 2662-7671