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Table 4 Effects of aqueous and methanol extracts of P. africanum on nitric oxide dosage

From: Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Treatment Dose (mg/kg) n [NO] Plasma (μmol/ml) [NO] Gastric supernatant (μmol/g)
Normal / 6 3.09 ± 0.24 9.18 ± 0.71*
Distilled water / 6 2.60 ± 0.22 12.96 ± 0.26
Maalox 50 6 3.40 ± 0.34 13.68 ± 0.67
Ranitidine 50 6 3.21 ± 0.33 7.66 ± 0.40**
Aqueous extract of P. africanum 125 6 1.64 ± 0.22* 16.91 ± 1.59**
250 6 2.10 ± 0.22 13.78 ± 0.65
500 6 2.71 ± 0.10 16.03 ± 0.76
Methanol extract of P. africanum 125 6 2.51 ± 0.17 15.23 ± 0.74
250 6 7.30 ± 0.51** 11.17 ± 0.42
500 6 4.65 ± 0.50** 13.88 ± 0.95
  1. n = number of animals per group, [NO] = Nitric oxide concentration, *Significant difference at 0,05 in relation to the control group having received distilled water, **Significant difference at 0,01 in relation to the control group having received distilled water