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Table 3 Effects of stem bark aqueous and methanol extracts of P. africanum on gastric ulcer induced by acetic acid

From: Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Treatment Dose (mg/kg) n US (mm2) Mucus weight (mg) I %
Normal / 6 0.00 ± 0.00** 107.00 ± 1.71* /
Distilled water / 6 94.07 ± 7.99 177.17 ± 7.67 /
Maalox 50 6 43.17 ± 1.05** 114.17 ± 1.14** 54.41
Ranitidine 50 6 12.56 ± 0.00** 109.00 ± 2.00** 86.73
Aqueous extract of P. africanum 125 6 37.95 ± 1.06** 130.17 ± 2.33** 59.92
250 6 15.04 ± 0.84** 126.00 ± 1.48** 84.12
500 6 38.21 ± 0.97** 134.50 ± 1.75** 59.65
Methanol extract P. africanum 125 6 28.00 ± 1.57** 151.17 ± 3.23** 70.43
250 6 42.15 ± 1.10** 147.67 ± 9.63** 55.49
500 6 40.16 ± 0.65** 139.33 ± 3.60** 57.59
  1. n = number of animals per group, US = ulcer surface, I % = inhibition percentage
  2. **Significant difference at 0,01 in relation to the control group having received distilled water