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Table 2 Effects of the stem bark aqueous and methanol extracts of Piptadeniastrum africanum on gastric lesions induced by indomethacin

From: Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Treatment

Dose (mg/kg)

n

US (mm2)

US %

UI

I %

Mucus weight (mg)

Distilled water

/

6

147.63ā€‰Ā±ā€‰5.58

10.05ā€‰Ā±ā€‰0.44

3.90ā€‰Ā±ā€‰0.29

/

45.33ā€‰Ā±ā€‰1.45

Maalox

50

6

71.80ā€‰Ā±ā€‰3.24**

4.82ā€‰Ā±ā€‰0.29**

1.94ā€‰Ā±ā€‰0.13**

51.36

47.50ā€‰Ā±ā€‰5.53

Misoprostol

0.10

6

43.81ā€‰Ā±ā€‰3.07**

3.18ā€‰Ā±ā€‰0.28**

1.57ā€‰Ā±ā€‰0.07**

70.36

45.67ā€‰Ā±ā€‰4.14

Aqueous extract of P. africanum

125

6

94.88ā€‰Ā±ā€‰0.93**

6.66ā€‰Ā±ā€‰0.20**

1.99ā€‰Ā±ā€‰0.15**

35.75

45.50ā€‰Ā±ā€‰1.98

250

6

70.37ā€‰Ā±ā€‰1.97**

4.49ā€‰Ā±ā€‰0.24**

2.11ā€‰Ā±ā€‰0.18**

52.23

63.00ā€‰Ā±ā€‰7.52

500

6

2.09ā€‰Ā±ā€‰2.09**

0.12ā€‰Ā±ā€‰0.12**

0.17ā€‰Ā±ā€‰0.17**

98.58

100.33ā€‰Ā±ā€‰10.08**

Methanol extract of P. africanum

125

6

97.86ā€‰Ā±ā€‰1.48**

6.21ā€‰Ā±ā€‰0.16**

2.53ā€‰Ā±ā€‰0.12**

33.71

53.50ā€‰Ā±ā€‰0.76

250

6

70.90ā€‰Ā±ā€‰3.03**

3.97ā€‰Ā±ā€‰0.15**

1.63ā€‰Ā±ā€‰0.05**

51.97

69.67ā€‰Ā±ā€‰2.19**

500

6

50.29ā€‰Ā±ā€‰2.75**

3.34ā€‰Ā±ā€‰0.21**

1.35ā€‰Ā±ā€‰0.05**

65.93

57.33ā€‰Ā±ā€‰1.31

  1. nā€‰=ā€‰number of animals per group, USā€‰=ā€‰Ulcer surface, US %ā€‰=ā€‰Ulcer surface percentages, UIā€‰=ā€‰Ulcer index, I %ā€‰=ā€‰inhibition percentage
  2. **Significant difference at 0,01 in relation to the control group having received distilled water