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Table 2 Effects of the stem bark aqueous and methanol extracts of Piptadeniastrum africanum on gastric lesions induced by indomethacin

From: Gastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats

Treatment Dose (mg/kg) n US (mm2) US % UI I % Mucus weight (mg)
Distilled water / 6 147.63 ± 5.58 10.05 ± 0.44 3.90 ± 0.29 / 45.33 ± 1.45
Maalox 50 6 71.80 ± 3.24** 4.82 ± 0.29** 1.94 ± 0.13** 51.36 47.50 ± 5.53
Misoprostol 0.10 6 43.81 ± 3.07** 3.18 ± 0.28** 1.57 ± 0.07** 70.36 45.67 ± 4.14
Aqueous extract of P. africanum 125 6 94.88 ± 0.93** 6.66 ± 0.20** 1.99 ± 0.15** 35.75 45.50 ± 1.98
250 6 70.37 ± 1.97** 4.49 ± 0.24** 2.11 ± 0.18** 52.23 63.00 ± 7.52
500 6 2.09 ± 2.09** 0.12 ± 0.12** 0.17 ± 0.17** 98.58 100.33 ± 10.08**
Methanol extract of P. africanum 125 6 97.86 ± 1.48** 6.21 ± 0.16** 2.53 ± 0.12** 33.71 53.50 ± 0.76
250 6 70.90 ± 3.03** 3.97 ± 0.15** 1.63 ± 0.05** 51.97 69.67 ± 2.19**
500 6 50.29 ± 2.75** 3.34 ± 0.21** 1.35 ± 0.05** 65.93 57.33 ± 1.31
  1. n = number of animals per group, US = Ulcer surface, US % = Ulcer surface percentages, UI = Ulcer index, I % = inhibition percentage
  2. **Significant difference at 0,01 in relation to the control group having received distilled water