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Table 1 Effects of L-Citrulline on metabolic parameters in SHRSP/ZF rat

From: L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1

   Control (n = 7) L-Citrulline (n = 7)
food intake (g) 0w 24.0 ± 0.5 24.7 ± 0.4
  4w 29.9 ± 0.5 29.4 ± 0.3
  8w 30.5 ± 2.2 29.5 ± 2.6
2.6body weight (g) 0w 121.9 ± 5.9 127.3 ± 4.2
  4w 330.7 ± 4.4 339.4 ± 7.6
  8w 420.5 ± 5.9 415.0 ± 12.2
serum    
insulin (ng/mL)   8.1 ± 3.6 10.8 ± 2.7
glucose (mg/dL)   280.2 ± 35.3 213.9 ± 16.6
triglyceride (mg/dL)   598.7 ± 99.5 594.4 ± 66.1
cholesterol (mg/dL)   94.6 ± 3.5 101.7 ± 3.0
free fatty acid (mEq/L)   1.8 ± 0.4 2.1 ± 0.4