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Table 1 Effects of L-Citrulline on metabolic parameters in SHRSP/ZF rat

From: L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1

  

Control (n = 7)

L-Citrulline (n = 7)

food intake (g)

0w

24.0 ± 0.5

24.7 ± 0.4

 

4w

29.9 ± 0.5

29.4 ± 0.3

 

8w

30.5 ± 2.2

29.5 ± 2.6

2.6body weight (g)

0w

121.9 ± 5.9

127.3 ± 4.2

 

4w

330.7 ± 4.4

339.4 ± 7.6

 

8w

420.5 ± 5.9

415.0 ± 12.2

serum

   

insulin (ng/mL)

 

8.1 ± 3.6

10.8 ± 2.7

glucose (mg/dL)

 

280.2 ± 35.3

213.9 ± 16.6

triglyceride (mg/dL)

 

598.7 ± 99.5

594.4 ± 66.1

cholesterol (mg/dL)

 

94.6 ± 3.5

101.7 ± 3.0

free fatty acid (mEq/L)

 

1.8 ± 0.4

2.1 ± 0.4