Effect of Uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model

Table 1 Purine levels in arthritic rats serum and treated for 45 days with Uncaria tomentosa extract

	C	E	A	A + E
	(log of nmol/ml)	(log of nmol/ml)	(log of nmol/ml)	(log of nmol/ml)
ATP	1.04 ± 0.003^a	1.02 ± 0.01^a	1.04 ± 0.02^a	0.89 ± 0.01^b
ADP	1.25 ± 0.002^a	1.28 ± 0.01^a	1.25 ± 0.01^a	1.34 ± 0.001^b
AMP	1.00 ± 0.005^a	1.05 ± 0.008^a	1.04 ± 0.008^a	1.02 ± 0.02^a
Adenosine	1.35 ± 0.001^a	1.29 ± 0.02^ab	1.33 ± 0.01^ab	1.11 ± 0.08^b

Adenine nucleotides and adenosine levels measurement in serum of Complete Freund’s Adjuvant (CFA)-induced arthritis rats and treated for 45 days with Uncaria tomentosa extract (150 mg/kg; 2 times/day). Purine levels measurement were log-transformed and are reported as log of nmol/ml. Groups: C (control), E (extract), A (arthritis) and A + E (arthritis + extract). Bars represent mean ± S.E.M
(^a,b) Indicates difference among the groups, P < 0.05 with n = 7 (two-way ANOVA-Newman-Keuls Multiple Comparison Test)