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Table 2 Effect of endophytic extracts (0.1 mg/mL) on the secretion of TNF-α in BV2 microglia cells1

From: Malaysian endophytic fungal extracts-induced anti-inflammation in Lipopolysaccharide-activated BV-2 microglia is associated with attenuation of NO production and, IL-6 and TNF-α expression

  TNF-α production (pg/mL)
  Unstimulated Stimulated with LPS
  24 h ± SEM 48 h ± SEM 24 h ± SEM 48 h ± SEM
BV2 33.84 ± 3.3 45.78 ± 13.5 4102.62 ± 999.7 2627.97 ± 432.3
HAB16R12 42.44 ± 21.7 61.80 ± 29.8 1150.71 ± 701.4* 1050.06 ± 577.7*
HAB16R13 43.33 ± 1.9 79.82 ± 2.7 960.88 ± 222.7* 982.20 ± 134.8*
HAB16R14 23.83 ± 4.6 58.51 ± 1.2 424.63 ± 98.0* 490.96 ± 86.7*
HAB16R18 32.22 ± 6.1 73.15 ± 0.9 1072.08 ± 332.7* 1052.11 ± 193.7*
HAB8R24 77.28 ± 6.4 103.56 ± 9.1 1511.54 ± 174.5* 1295.21 ± 265.6*
  1. 1Data are expressed as means ± SEM of three independent experiments. *P < 0.05, significantly different when compared to LPS-treated control (BV2)