Fig. 3From: A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitroEffect of lupane on the development of Leishmania (L.) amazonensis within peritoneal macrophage. Infected mouse peritoneal macrophages were treated with 109 μM of lupane or 546,5 μM of Glucantime® for up to 96 h. The survival index (a) and the number of intracellular amastigotes (b) was determined at the indicated times. Each bar represents the mean ± standard error of at least three independent experiments, which were performed in duplicate. Statistically significant differences (p ≤ 0.05) between treated and non-treated groups are indicated by (*)Back to article page