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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Partially purified components of Uncaria sinensis attenuate blood brain barrier disruption after ischemic brain injury in mice

Fig. 3

Evans blue extravasation was attenuated in PPUS-treated mice after ischemic brain injury. (a) Representative photographs of Evans blue leakage in coronal section of the brain in vehicle (Veh)- and partially purified component of Uncaria sinensis (PPUS)-treated mice 24 h after photothrombotic cortical ischemia. Mice were intraperitoneally administered DMSO or 1 mg/kg PPUS 30 min before ischemic insult. Blue area shows extravasated Evans blue, indicating BBB disruption. (b) Quantitative analysis of Evans blue leakage. Data are expressed as means ± SEM (N = 5). ** P < 0.01 compared with the vehicle group (One-way ANOVA)

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