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Table 1 Effect of different extracts of Kaempferia galanga on thiopental sodium induced sleeping time test in mice

From: Study of sedative activity of different extracts of Kaempferia galanga in Swiss albino mice

Group

Dose (mg/kg)

Onset of Sleep (minutes)

Duration of Sleep (minutes)

Percent effect

Control

5 ml/kg

2.06 ± 0.64

66.33 ± 8.04

100

Diazepam

2

1.36 ± 0.06

153.5 ± 11.53**

231.42

ACR

100

1.83 ± 0.38

83.33 ± 2.36

125.63

200

1.67 ± 0.12

183.5 ± 21.40**

276.65

PEF

100

1.77 ± 0.18

105 ± 6.99

158.29

200

1.89 ± 0.43

164.17 ± 17.61**

247.50

CHF

100

1.87 ± 0..25

97.67 ± 20.08

147.25

200

1.28 ± 0.22

237.83 ± 8.09**

358.55

MEF

100

1.92 ± 0.23

95.17 ± 16.25

143.48

200

1.51 ± 0.13

176.83 ± 24.57**

266.59

ACL

100

1.91 ± 0.24

69.5 ± 4.09

104.78

200

1.41 ± 0.06

113.5 ± 15.65*

171.11

  1. Control group received water 5 ml/kg (p.o), standard group received Diazepam 2 mg/kg body weight (i.p.), test groups ACR, PEF, CHF, MEF and ACL were treated with 100 and 200 mg/kg body weight of the extracts (p.o.) respectively. Values are mean ± SEM, (n = 6); * p < 0.05, **p < 0.001, Dunnett t-test as compared to control. ACR = Acetone extract of rhizome, PEF = Petroleum ether fraction of rhizome, CHF = Chloroform fraction of rhizome, MEF = Methanol fraction of rhizome and ACL = Acetone extract of leaf